The proposal “Housing and Health Vulnerability of the Elderly in Italy” (VAI) has two macro-objectives: to produce (OB1) and promote (OB2) new knowledge on housing and health vulnerability of the elderly, with a sensitive view to the territorial dimension and socioeconomic inequalities. VAI incorporates an innovative inter-disciplinary research perspective, which intends to go beyond the state of the art, integrating knowledge and methodologies that refer to different scientific backgrounds, developing a real intersection, and not a mere juxtaposition of approaches, in order to capture the multidimensionality of the phenomena investigated.