In line with the objectives of the International Network on Health Literacy initiative and the Age-It program, the PROMETEO project intends to extend the analysis of health literacy in Italy in the regional context of Puglia through the implementation of a cross-sectional clinical study. With reference to the population over 65 years old afferent to territorial and hospital health services in the Apulian provinces, the PROMETEO project aims to analyze the level of health literacy in general and with reference to communication with physicians in the context of health services. It will also analyze the main sources used to acquire information about managing one's own health and compare the effectiveness of different dissemination strategies of the results obtained.