ACTIVAGE is a project designed to study the role of physical activity (PA) on healthy aging (HA). We will use a longitudinal cohort to investigate clinical outcomes, functional levels of HA, physical performance, and biomarkers of aging. The study will follow elderly patients with acute cardiac events (MI), pre-elderly and elderly without MI, randomly assigned to treatment (PA + health education) or control (health education only) groups. Specifically, the following aspects will be monitored: cardiac health and HA levels; Physical performance; Biomarkers of aging (circulating and systemic). In addition, we will investigate the molecular mechanisms that explain the effects of PA on HA (WP4).Finally, we will engage in a qualitative study to analyze patients' perceptions of the proposed intervention, identify barriers to transferability, and conduct a cost-benefit analysis to measure its economic impact.