Leader: Giuseppe Passarino (UNICAL); Other collaborator(s): Francesca Cavalcanti, Antonio Procopio, Anna Napoli, Graziano Pesole, Serena Sanna, Leonardo Tenori, Marco Bianchi, Licia Iacoviello, Veronica De Rosa, Sofia Pavanello.
The WP4 uses different high throuput approaches to identify molecular mechanisms associated to aging-specific features, to ageing trajectories and to ageing hallmarks. In particular the different groups involved will carry out epigentic analyses, proteomic analyses, analysis of microbiomes, high performace analysis of electrocardiograms. It is worth mentioning that the AGE-IT Project allows to have the possibility to compare analogous results obtained in different groups of subject, but also to have different approaches on the same subjects to find out the correlation among the different mechanisms associated to ageing.